Case Review in Neuro-Oncology

Intro

 

A right-handed 43-year-old white female, previously healthy, presented with a generalized tonic clonic seizure and was admitted to the neurology service. Following her seizures, she recovered completely and was neurologically intact.

She complained of headache requiring management with decadron. An MRI was obtained and showed two lesions hyperintense on FLAIR (Fig. 1 a, b, c) — a large right temporal non-enhancing lesion and a second lesion in the cingulate gyrus with patchy enhancement (Fig. 2).

 

The patient underwent extensive work-up by neurology with negative lumbar puncture results. MRI spectroscopy and perfusion then was obtained and showed results of elevated choline: creatinine ratio in both lesions and elevated perfusion consistent with tumor, likely glioma.

tumorsectionpoll.png